Journal

Longevity

Cold Therapy and Longevity

Hormesis, mitochondrial biogenesis and the emerging science of stress that extends healthspan.

Author

Dr. Ingrid Halvorsen

Physiology Advisor

Published

February 2026

Reading

10 min read

Longevity is no longer a fringe conversation. It is a category of medicine, and cold exposure sits comfortably inside its evidence-based toolkit.

Hormesis

A brief, controlled stressor triggers an adaptive response that leaves the system stronger. Cold, heat, fasting and exercise all share this shape.

A brief, controlled stressor leaves the system stronger. Cold, heat, fasting and exercise all share this shape.

Mitochondrial signalling

Cold exposure appears to upregulate mitochondrial biogenesis pathways, a mechanism of interest for cellular energy and healthspan.

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